AFE is the second leading cause of maternal death in the US and Europe Signs/ symptoms of AFE include respiratory distress, cardiovascular collapse, and coagulopathy. Maternal treatment is primarily supportive, whereas prompt delivery of the mother who has sustained cardiopulmonary arrest is critical for improved newborn outcome. Amniotic fluid embolism (AFE) is a complication of pregnancy where amniotic fluid enters the maternal pulmonary circulation causing sudden cardiovascular collapse. Amniotic fluid embolism (AFE) is a rare, catastrophic obstetric emergency that can present with sudden maternal collapse, associated with hypoxaemia. Data regarding the presence of risk factors for amniotic fluid embolism are inconsistent and contradictory at present, no putative risk factor has been identified that would justify modification of standard obstetric practice to reduce the risk of this condition. Coughing, with or without blood, can occur in people with pulmonary embolism because the blockage can cause fluid to build up in the lungs (pulmonary edema). Amniotic fluid embolism (AFE) is a rare, severe maternal complication with an incidence of 0.0010.013 1,2, and the mortality rate is very high (3780) 3,4.AFE reportedly causes 24.3 of all. Amniotic fluid embolism (AFE) is a rare obstetric syndrome in pregnant women that results in acute circulatory failure and disseminated intra-vascular. Clinical series based on population or administrative databases that do not include individual chart review by individuals with expertise in critical care obstetrics are likely to both overestimate the incidence and underestimate the mortality of this condition by the inclusion of women who did not have amniotic fluid embolism. Progress in our understanding of this syndrome continues to be hampered by a lack of universally acknowledged diagnostic criteria, the clinical similarities of this condition to other types of acute critical maternal illness, and the presence of a broad spectrum of disease severity. This response and its subsequent injury appear to involve activation of proinflammatory mediators similar to that seen with the classic systemic inflammatory response syndrome. 80 of individuals with AFE develop DIC 3. The pathophysiology appears to involve an abnormal maternal response to fetal tissue exposure associated with breaches of the maternal–fetal physiologic barrier during parturition. Amniotic fluid embolism is when some of your baby’s cells or amniotic fluid (fluid that surrounds the baby in the womb) gets into the bloodstream. Amniotic fluid embolism syndrome (AFES) is another complication of pregnancy. Amniotic fluid embolism remains one of the most devastating conditions in obstetric practice with an incidence of approximately 1 in 40,000 deliveries and a reported mortality rate ranging from 20% to 60%. Ten percent (6/59) of the women with typical amniotic fluid embolism had a pregnancy complicated by placenta previa, and 8 (5/61) had undergone in vitro.
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